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Medication 

 

These are all they types of medication I take which has helped me throughout the years which i will list below. I believe that a combination of the below have helped me to relieve symptoms I've been facing since being diagnosed with mitochondrial disease. I take one of each of these every day. 

 

Bisoprolol 

​Is a class of medication called 'Beta blockers'. It works by relaxing the blood vessels and slowing the heart rate to help improve and decrease blood the pressures. 

Lisinopril 

This medication is used along side Bisoprolol to help treat my heart problem. They work well together. I take 2.5mg Lisinopril every day to help to try and stabilize and keep my heart as strong as possible. 

 

Co Enzyme Q10

​​Coenzyme Q10 (CoQ10) is a tablets that helps convert food into energy. CoQ10 is found in almost every cell in the body, and it is a powerful antioxidant. I take two of these a day (total of 200mg). From google it states "CoQ10 is a natural antioxidant present in mitochondrial membranes that helps protect cells from oxidative stress-induced damage. In their review, the authors highlight studies in which supplementation with CoQ10 has led to symptomatic relief of fatigue and pain in individuals with fibromyalgia."

Niacinamide 

Niacinamide a form of vitamin B3 (niacin).I take one of these a day.  There are eight types of B Vitamins and niacinamide is one of them. Vitamin B3 is essential to maintain good body health. taking one of these a day helps Vitamin B3 helps converts the foods we eat into energy. ​​

Omega 3 fish oil triple strength tablets 

Fish oil is an excellent source of omega-3, which is good for the heart and the brain. However, getting your omega-3s from fish is healthier. If you don’t eat fish, fish oil supplements are a good alternative (330mg)

​​

 Urolithin A Supplement 

​ The reason I take Urolithin A ia because Urolithin A (UA) is a natural compound that can improve mitochondrial health and function, and may help with a number of conditions such as ​

 

Mitochondrial health 

UA can improve mitochondrial health in humans through regular oral consumption. It can also increase mitochondrial gene expression in older humans. ​

 

Muscle health

UA can improve muscle function and strength in older animals and humans. It can also increase aerobic endurance in young rats. 

 

Osteoarthritis (OA)

  • UA can reduce cartilage degeneration and alleviate pain in OA. It can also decrease synovitis, an inflammation of the synovial membrane that is a component of OA pathology. 

  • Auditory cell senescence

  • UA can attenuate auditory cell senescence by activating mitophagy. 

  • UA is a gut microbiome-derived food metabolite that stimulates mitophagy, which is the process of removing old mitochondria that contribute to cellular dysfunction. 

 

 I take 2 x Urolithin A Supplement is a tablet which I have recently started taking to help me (total 2000mg)

Medicine I've been told i should avoid:

Please be aware this is not for everyone this is just what i have been told 

  • Amiodarone

  • Antibiotics: Gentamicin, chloramphenicol,  tetracycline

  • Anti-cancer medicines: doxorubicin, cisplatin

  • Local anaesthetics: bupivicane, lidocaine

  • Metformin

  • Nicotine

  • Non-steroidal anti-inflammatory drugs:
    ibuprofen, diclofenac, naproxen

  • Nucleoside reverse transcriptase inhibitors:
    zidovudine, didanosine, lamivudine, abacavir

  • Paracetamol (overdose)

  • Phenytoin

  • Pioglitazone

  • Simvastatin (other statins have weaker effects

  • Antipsychotics: haloperidol, risperidone, clozapine

  • Aspirin

  • Beta-blockers: metoprolol, propranolol

  • Ciprofibrate

  • Corticosteroids

  • Fluoxetine

  • Isoflurane

  • Isoflurane / halothane / sevoflurane

  • Linezolid

  • Propofol (particularly > 4 mg/kg/h for > 48 hours)

  • Sertraline

  • Tricyclic antidepressants:

  • amitriptyline, clomipramine

  • Sodium valproat

DISCLAIMER

This by no means meant to be medical advice, I do what works for me through my own research and if you or someone you know suffers from this condition then hopefully some of this information will help guide you, or give you ideas, but I am not a medical professional and my family have basically done their own research, read medical papers and tests and we do what is best for me medication wise and diet wise.

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